ABSTRACT
Oral cancer is not only a serious threat to human health and life but also its incidence rate has been increasing year by year. Oral cancer animal model is indispensable for the research of clinical diagnosis and treatment of oral cancer. Therefore, it is of great importance to establish an animal model of disease which is similar to the natural occurrence of human oral cancer and to study its pathogenesis, prevention and treatment. At present, animal models of oral cancer mainly include spontaneous animal model, induced animal model and genetically modified animal model. The research progress, current problems and the future development perspectives of animal models of oral cancer in recent years are summarized in this paper.
ABSTRACT
Cartilage apoptosis functions a lot in OA occurrence.Its apoptosis has two ways of NO and Fas,mainly controlled by Bcl-2 gene family,Bax,P53,ICE and c-myc gene family;the degeneration of cartilage cell base can induce apoptosis.It shows cartilage apoptosis function in OA occurrence,helpful to prevention and treatment of OA.
ABSTRACT
Objective To introduce the method, indications and the usage of abdominal double layer subcutaneous flap for the repair of late complicated hand injury. Methods A new type of flap was designed to repair the complicated hand injury. Sixteen cases were treated with this method since 1998. Results The duration of the follow up ranged from 3 to 24 months with an average of 13 months. All of the flaps survived well. After physiotherapy, the overall excellent and good rate of joint movement was 80%(TAM standard). No further surgery was required in all of the cases. Conclusion The abdominal double layer subcutaneous flap was especially indicated in those cases with bone nonunion, tendon and nerve defect and tendonous adhesions. This kind of flap not only provide a good skin covering, but also offer a soft bed for the tendons, nerves, and bones.
ABSTRACT
Objective Twenty- four case of non- traumatic paralysis of radial nerve were reviewed. Methods Between 1985 and 2000, 24 patients with non- traumatic paralysis of radial nerve were referred to this hospital for treatment. There were 18 men and 6 women with a mean age of 38 years (range, 10 to 65 years). Eleven patients had occupations with unduly stress of the forearm. Tendon transfer was performed in 1 patient, operative neurolysis in 18, nerve- grafting in 3, neurorrhaphy in 2. Results Of the 12 patients with the palsy attributed to entrapment of the fibrous edge of muscles, 8 occurred at the supinator, 1 at the tendinous edge of extensor digitorum communis and 3 at multiple sites.The palsy was caused by marked constrictions of the nerves in 5 patients, by benign tumors or tumorous conditions in 4 (by a ganglion in 2, by lipoma in 1 and by haemangioma in 1), by a neurilemmoma on the nerve in 1. The cause was unknown in 1. The patients who accepted neurolysis were followed up from 6 months to 15 years postoperatively. An excellent or good functional result was documented in 14 patients, fair in 3, and poor in 1. The patients who were treated with neurorrhaphy or nerve- grafting were followed- up from 4 months to 6 years, 3 recovered completely, 2 were in the convalescent stage (1 was treated by nerve- grafting and the other by neurorrhaphy). Conclusion The etiology of non- traumatic paralysis of radial nerve was miscellaneous. The results of surgical treatment were satisfactory.